Single-Cell Multiomics Presentations at ASH Annual Meeting & Expo

To gain real-world insight into how our customers utilize Mission Bio's technology and the Tapestri Platform, check out the scientific workshops, oral presentations, and posters presented at the conference below.

If you'd like to schedule a one-on-one meeting with our team to learn more, fill out the short form on the right.

 

SCIENTIFIC WORKSHOPS

"Single-Cell Multiomics in Myelodysplastic Syndromes and Acute Myeloid Leukemia Upon Treatment with Hypomethylating Agents" Manel Esteller. Details

 

ORAL PRESENTATIONS

120: "Clonal Targeting of DNA Damage Response Pathways Eradicates Myeloproliferative Neoplasms." Monika Toma. Details

423: "Venetoclax Has Potent Efficacy in NPM1 mutated AML with Acquired Resistance Associated with Either Perturbed Pro-Survival Signalling or NPM1 wild-Type Populations." Chong Chyn Chua. Details

514: "Mutant Natural Killer Cell Dysfunction Enables the Immune Escape of Premalignant MDS Cell Clones." Irene Ganan-Gomez. Details

705: "Branching Trajectories and Diversification of Clonal Escape in Aplastic Anemia Revealed By Single-Cell Genomics." Masanori Yoshida. Details

747: "Bomedemstat (IMG-7289), an LSD1 Inhibitor, Manages the Signs and Symptoms of Essential Thrombocythemia (ET) While Reducing the Burden of Cells Homozygous for Driver Mutations." Joachim R. Goethert. Details

996: "Divergent Functions of ERK2 Substrate Binding Modalities in Myeloproliferative Neoplasm." Billy Truong. Details

 

POSTERS

1317: "Clonal Hematopoiesis in Whole-Blood and Cell-Free DNA of Ovarian Cancer Patients Undergoing PARP-Inhibitor Treatment: An Exploratory Analysis of the ENGOT-ov48/Eudario Trial." Christopher Maximilian Arends. Details

1575: "BRAF-Mutated Acute Myeloid Leukemia (AML) Represents a Distinct, Prognostically Poor Subgroup Enriched in Myelodysplasia-Related (MR-)AML." Yazan Abu-Shihab. Details

1593: "Precise Single-Cell Transcriptomic Mapping of Leukemia Cell States Reveals Unconventional Lineage Priming in Acute Myeloid Leukemia." Andy G.X. Zeng. Details

1606: "Clonal Heterogeneity and Evolution during Treatment in High Hyperdiploid B-Cell Acute Lymphoblastic Leukemia." Margo Aertgeerts. Details

1784: "Leukemic Driver Clones Can Arise Independently and Outcompete MPN Cells in Post-MPN Secondary AML." Tyler M Parsons. Details

2688: "BAX Mutated Clonal Hematopoiesis Arises Following Treatment with the BCL2 Inhibitor Class of Therapeutics across a Range of Hematological and Non-Hematological Neoplasms." Ing Soo Tiong. Details

2931: "Single-Cell Proteogenomics Analysis of AML Samples Treated with Decitabine and Venetoclax Reveals Divergent Treatment Escape Mechanisms." Yi June Kim. Details

2958: "Minimal Residual Disease Detection By Single Cell DNA Sequencing Technology: A Feasible Approach for Clinical Application and Identification of the Landscape of MRD Clones." Ana Alfonso Pierola. Details

3003: "A Multi-Omic Study Unveils a Clonal Population of TET2-Mutated Infiltrating T-Cells in Germinal Center B Cell Lymphomas (DLBCL and FL)." Sofia Huerga. Details

3580: "Integrative Single-Cell Tracking of Clonal Evolution, Leukemia Phenotypes and Donor Engraftment Following Allogeneic Stem Cell Transplant Using Mitochondrial DNA Mutations." Livius Penter. Details

4116: "Multiomic Characterization of Myelodysplastic Neoplasms (MDS) with Micromegakaryocytes Highlights the Role of EZH2-RUNX1 deregulation in Disease Physiopathology and Response to Targeted Therapies." Miranda Fernandez-Serrano. Details

4135: "First-Hit SETBP1 Mutations Cause a Myeloproliferative Disorder with Bone Marrow Fibrosis." Ilaria Crespiatico. Details

4301: "Clonal Medicine Targeting DNA Damage Response Eradicates AML." Monika Toma. Details

4257: "Venetoclax Combined with "7+3" Induction Chemotherapy Induces High Rates of MRD-Negative Remission in Newly Diagnosed AML Patients Fit for Intensive Chemotherapy Irrespective of Age." Ioannis Mantzaris. Details

4334: "Multiomic Single-Cell Sequencing May Distinguish BCR-ABL-Mutated Acute Myeloid Leukemia (AML) from Blast Crisis Chronic Myelogenous Leukemia (BC-CML)." Vanessa E. Kennedy. Details

4714: "Single Cell Multi-Omic Correlation of Single Nucleotide Variants, Copy Number Variation and Surface Epitopes for Clonal Profiling of Myeloma." Adam Sciambi. Details

5014: "Single-Cell Genomics and Proteomics Reveals Venetoclax-Resistant Monocytic Differentiation of TP53 LOH Clones in TP53 Mutant AML." Edward Ayoub. Details

 

EDUCATION PROGRAMS

"Clonal Hematopoiesis in Frequent Whole Blood Donors" Darja Karpova. Details

 

Download the list of presentations

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